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. 2016 Nov 13;30(17):2729-2730.
doi: 10.1097/QAD.0000000000001254.

In-utero exposure to nelfinavir-ethyl methyl sulfone

Mira Hleyhel  1 , Stéphanie Goujon, Jeanne Sibiude, Stéphane Blanche, Josiane Warszawski; on behalf the ANRS French Perinatal Cohort study Group
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In-utero exposure to nelfinavir-ethyl methyl sulfone

Mira Hleyhel et al. AIDS. .

Abstract

Ethyl methyl sulfone contained in nelfinavir between 2007 and 2008 accidentally exposed embryos and fetuses to a powerful mutagen. We report data for 101 HIV-uninfected children exposed in utero included in the French prospective national cohort. The incidence of malformation was similar to that in the cohort as a whole with different drug exposures; no children had developed cancer after 9 years of follow-up.

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