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. 2016:2016:6267406.
doi: 10.1155/2016/6267406. Epub 2016 Sep 7.

Medication-Related Osteonecrosis of Jaws: A Low-Level Laser Therapy and Antimicrobial Photodynamic Therapy Case Approach

Mariana Comparotto Minamisako  1 , Guilherme Henrique Ribeiro  2 , Mariáh Luz Lisboa  2 , Mabel Mariela Rodríguez Cordeiro  3 , Liliane Janete Grando  4
Affiliations

Medication-Related Osteonecrosis of Jaws: A Low-Level Laser Therapy and Antimicrobial Photodynamic Therapy Case Approach

Mariana Comparotto Minamisako et al. Case Rep Dent. 2016.

Abstract

Medication-related osteonecrosis of the jaws (MRONJ) can be considered an inability of the alveolar bone to respond to an injury, which frequently leads to severe local and systemic complications. Once the problem is installed, dentist must use all therapeutic approaches recommended. This manuscript reports a successful management of MRONJ handled with antibiotics, conservative debridement, low-level laser therapy (LLLT), and photodynamic therapy (PDT) up to 12 months. As healing of MRONJ may be very slow, combined therapeutic approaches are required. Besides the recommended conventional treatment protocol, LLLT and PDT are important tools to contribute to healing and improvement of patient's quality of life.

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Figures

Figure 1
Figure 1
Clinical aspect of bone exposure measuring approximately 1.5 cm at vestibular sulcus of right maxilla (a). CT showing bone lysis and necrotic bone sequestrum at maxilla with oral antral communication risk (b). Clinical aspect of vestibular sulcus mucosa totally recovered after 37 sessions of LLLT and PDT (c).
See this image and copyright information in PMC

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