Remote ischemic preconditioning to prevent cardiac surgery-related acute kidney injury: how far away from a breakthrough?

Affiliations

Editorial

Patrick M Honore et al. Ann Transl Med. 2016 Aug.

. 2016 Aug;4(16):314.

doi: 10.21037/atm.2016.08.10.

¹ ICU Department, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium.

No abstract available

Conflict of interest statement

The authors have no conflicts of interest to declare.

Effect of remote ischemic preconditioning on kidney injury among high-risk patients undergoing cardiac surgery: a randomized clinical trial.
Zarbock A, Schmidt C, Van Aken H, Wempe C, Martens S, Zahn PK, Wolf B, Goebel U, Schwer CI, Rosenberger P, Haeberle H, Görlich D, Kellum JA, Meersch M; RenalRIPC Investigators. Zarbock A, et al. JAMA. 2015 Jun 2;313(21):2133-41. doi: 10.1001/jama.2015.4189. JAMA. 2015. PMID: 26024502 Clinical Trial.

1. O'Neal JB, Shaw AD, Billings FT, 4th. Acute kidney injury following cardiac surgery: current understanding and future directions. Crit Care 2016;20:187. 10.1186/s13054-016-1352-z - DOI - PMC - PubMed
1. Gomez H, Ince C, De Backer D, et al. A unified theory of sepsis-induced acute kidney injury: inflammation, microcirculatory dysfunction, bioenergetics, and the tubular cell adaptation to injury. Shock 2014;41:3-11. 10.1097/SHK.0000000000000052 - DOI - PMC - PubMed
1. Lagny MG, Jouret F, Koch JN, et al. Incidence and outcomes of acute kidney injury after cardiac surgery using either criteria of the RIFLE classification. BMC Nephrol 2015;16:76. 10.1186/s12882-015-0066-9 - DOI - PMC - PubMed
1. Przyklenk K, Whittaker P. Remote ischemic preconditioning: current knowledge, unresolved questions, and future priorities. J Cardiovasc Pharmacol Ther 2011;16:255-9. 10.1177/1074248411409040 - DOI - PubMed
1. Hausenloy DJ, Yellon DM. Remote ischaemic preconditioning: underlying mechanisms and clinical application. Cardiovasc Res 2008;79:377-86. 10.1093/cvr/cvn114 - DOI - PubMed