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Review
. 2017 Apr 19;35(17):2217-2223.
doi: 10.1016/j.vaccine.2016.08.045. Epub 2016 Sep 23.

Improving cold chain systems: Challenges and solutions

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Free article
Review

Improving cold chain systems: Challenges and solutions

Ashvin Ashok et al. Vaccine. .
Free article

Abstract

While a number of new vaccines have been rolled out across the developing world (with more vaccines in the pipeline), cold chain systems are struggling to efficiently support national immunization programs in ensuring the availability of safe and potent vaccines. This article reflects on the Clinton Health Access Initiative, Inc. (CHAI) experience working since 2010 with national immunization programs and partners to improve vaccines cold chains in 10 countries-Ethiopia, Nigeria, Kenya, Malawi, Tanzania, Uganda, Cameroon, Mozambique, Lesotho and India - to identify the root causes and solutions for three common issues limiting cold chain performance. Key recommendations include: Collectively, the solutions detailed in this article chart a path to substantially improving the performance of the cold chain. Combined with an enabling global and in-country environment, it is possible to eliminate cold chain issues as a substantial barrier to effective and full immunization coverage over the next few years.

Keywords: Cold chain capacity; Cold chain equipment maintenance; Cold chain technology; Immunization supply chain; Temperature monitoring; Vaccine cold chain.

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