Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2016 Sep 20:26:10.
doi: 10.1186/s12610-016-0037-4. eCollection 2016.

Zinner's syndrome: report of two cases and review of the literature

Affiliations
Case Reports

Zinner's syndrome: report of two cases and review of the literature

Amine Slaoui et al. Basic Clin Androl. .

Abstract

Background: Congenital malformations of the seminal vesicle are uncommon, and most of them are cystic malformations. If an insult occurs between the 4th and the 13 h gestational week, the embryogenesis of the kidney, ureter, seminal vesicle, and vas deferens could be altered. Cysts of the seminal vesicle may appear with a mass effect, dysuria, epididymitis, or obstruction of the gastrointestinal and genitourinary tracts. Approximately two thirds of them are associated with ipsilateral renal agenesis, because both the ureteral buds and seminal vesicles originate from the mesonephric (Wolffian) duct. They were first described by Zinner in 1914, and 200 cases of seminal vesicle cysts associated with ipsilateral renal agenesis have been reported in the literature. Most patients with this anomaly are asymptomatic until the third or fourth decade of life. Some cases have nonspecific symptoms such as prostatism, urinary urgency, dysuria, painful ejaculation, and perineal discomfort. Transrectal ultrasonography provides good visualization of the pelvic structures and allows guidance for aspiration of the cysts.

Case presentation: We present two cases of seminal vesicle cyst. The first patient had dysuria, increased frequency of urination, and haematuria. He was operated and benefited from a removal of the cyst with right ureterectomy and left ureteral reimplantation. The second patient had disorder of the digestive transit and he benefited from a laparoscopic removal of the cyst.

Conclusions: Seminal vesicle cysts combined with ipsilateral renal agenesis are rare urological anomalies. Usual symptoms that are caused by the seminal vesicle cysts are bladder irritation and obstruction as well as pain in the perineum and scrotum. Epididymitis is frequently found. Treatment consists to removing the seminal vesicle cyst.

Keywords: Ipsilateral renal agenesis; Seminal vesicle cysts; Zinner’s syndrome.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
CT image showing a homogeneous liquid mass to polylobed contours not taking contrast retrovesical
Fig. 2
Fig. 2
CT image showing a single right kidney
Fig. 3
Fig. 3
Pelvic MRI showing retrovesical cyst, limited training well lateralized left coarsely rounded (56 × 54 × 44) with thin wall
Fig. 4
Fig. 4
Pelvic MRI showing the cyst (Sagittal section)
Fig. 5
Fig. 5
Image intraoperative (laparoscopic): retrovesical cyst

References

    1. Zinner A. Ein fall von intravesikaler samenblasenzyste. Weien Med Wschr. 1914;64:604–10.
    1. Pereira BJ, Sousa L, Azinhais P, Conceição P, Borges R, Leão R, Brandão A, Temido P, Retroz E, Sobral F. Zinner’s syndrome: an up-to-date review of the literature based on a clinical case. Andrologia. 2009;41(5):322–30. doi: 10.1111/j.1439-0272.2009.00939.x. - DOI - PubMed
    1. Rappe BJM, Meuleman EJH, Debruyne FMJ. Seminal vesicle cyst with ipsilateral renal agenesis. Urol Int. 1993;50(1):54–6. doi: 10.1159/000282451. - DOI - PubMed
    1. Heaney JA, Pfister RC, Meares EM., Jr Giant cyst of the seminal vesicle with renal agenesis. AJR Am J Roentgenol. 1987;149(1):139–40. doi: 10.2214/ajr.149.1.139. - DOI - PubMed
    1. Kenney PJ, Leeson MD. Congenital anomalies of the seminal vesicles: spectrum of computed tomographic findings. Radiology. 1983;149(1):247–51. doi: 10.1148/radiology.149.1.6611933. - DOI - PubMed

Publication types

LinkOut - more resources