Anal Squamous Intraepithelial Lesions and HPV Among Young Black Men Who Have Sex with Men
- PMID: 27673362
- PMCID: PMC5278831
- DOI: 10.1089/lgbt.2016.0049
Anal Squamous Intraepithelial Lesions and HPV Among Young Black Men Who Have Sex with Men
Abstract
Purpose: Limited data are available on anal squamous intraepithelial lesions (ASILs) and anal human papillomavirus (HPV) infection in young, Black populations. The purpose of this study was to examine the prevalence of and relationships between ASILs and high-risk HPV infection in a young (<30 years of age), predominantly Black, men who have sex with men (MSM) population.
Methods: Results of anal cytology and HPV DNA were gathered for 83 individuals.
Results: Forty-two percent of individuals (35) had atypical squamous cells of undetermined significance and 33% (27) had low-grade squamous intraepithelial lesion by cytology. Only 9% tested positive for both high-risk HPV subtypes 16 and 18.
Conclusion: Low rates of infection with both HPV types 16 and 18 may provide further evidence that we should continue to vaccinate young, Black MSM against HPV.
Keywords: HIV/AIDS; cancer; epidemiology; health screening; men who have sex with men (MSM); prevention.
Conflict of interest statement
Author Disclosure Statement No competing financial interests exist.
Similar articles
-
Cytological Anal Squamous Intraepithelial Lesions Associated with Anal High-Risk Human Papillomavirus Infections among Men Who Have Sex with Men in Northern Thailand.PLoS One. 2016 May 26;11(5):e0156280. doi: 10.1371/journal.pone.0156280. eCollection 2016. PLoS One. 2016. PMID: 27227684 Free PMC article.
-
Natural History of Anal Squamous Intraepithelial Lesions in HIV-Positive Men with Normal Baseline Cytology.AIDS Patient Care STDS. 2019 Nov;33(11):459-465. doi: 10.1089/apc.2019.0186. AIDS Patient Care STDS. 2019. PMID: 31682165
-
Human papillomavirus prevalence in the anus and urine among HIV-infected Japanese men who have sex with men.J Infect Chemother. 2017 Sep;23(9):621-626. doi: 10.1016/j.jiac.2017.06.005. Epub 2017 Jul 6. J Infect Chemother. 2017. PMID: 28688605
-
Anal human papillomavirus infection among HIV-infected and uninfected men who have sex with men in Beijing, China.J Acquir Immune Defic Syndr. 2013 Sep 1;64(1):103-14. doi: 10.1097/QAI.0b013e31829b6298. J Acquir Immune Defic Syndr. 2013. PMID: 23732908 Free PMC article.
-
Human papillomavirus infection & anal cytological abnormalities in HIV-positive men in eastern India.BMC Infect Dis. 2018 Dec 27;18(1):692. doi: 10.1186/s12879-018-3618-3. BMC Infect Dis. 2018. PMID: 30587145 Free PMC article.
Cited by
-
High prevalence of vaccine-preventable anal human papillomavirus infections is associated with HIV infection among gay, bisexual, and men who have sex with men in Nairobi, Kenya.Cancer Med. 2023 Jun;12(12):13745-13757. doi: 10.1002/cam4.6008. Epub 2023 May 4. Cancer Med. 2023. PMID: 37140209 Free PMC article.
-
High Prevalence of Anal Oncogenic Human Papillomavirus Infection in Young Men Who Have Sex with Men Living in Bamako, Mali.Infect Agent Cancer. 2021 Jul 1;16(1):51. doi: 10.1186/s13027-021-00385-0. Infect Agent Cancer. 2021. PMID: 34210322 Free PMC article.
-
Unusual and unique distribution of anal high-risk human papillomavirus (HR-HPV) among men who have sex with men living in the Central African Republic.PLoS One. 2018 May 24;13(5):e0197845. doi: 10.1371/journal.pone.0197845. eCollection 2018. PLoS One. 2018. PMID: 29795661 Free PMC article.
-
Pre-vaccination prevalence of anogenital and oral human papillomavirus in young HIV-infected men who have sex with men.Papillomavirus Res. 2019 Jun;7:52-61. doi: 10.1016/j.pvr.2019.01.002. Epub 2019 Jan 15. Papillomavirus Res. 2019. PMID: 30658128 Free PMC article. Clinical Trial.
-
Prevalence of and Risk Factors for Anal Human Papillomavirus Infection in a Sample of Young, Predominantly Black Men Who Have Sex With Men, Houston, Texas.J Infect Dis. 2018 Feb 14;217(5):777-784. doi: 10.1093/infdis/jix617. J Infect Dis. 2018. PMID: 29216355 Free PMC article.
References
-
- Conley L, Bush T, Darragh TM, et al. : Factors associated with prevalent abnormal anal cytology in a large cohort of HIV-infected adults in the United States. J Infect Dis 2010;202:1567–1576 - PubMed
-
- de Pokomandy A, Rouleau D, Ghattas G, et al. : HAART and progression to high-grade anal intraepithelial neoplasia in men who have sex with men and are infected with HIV. Clin Infect Dis 2011;52:1174–1181 - PubMed
-
- Machalek DA, Poynten M, Jin F, et al. : Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: A systematic review and meta-analysis. Lancet Oncol 2012;13:487–500 - PubMed
-
- Salit IE, Lytwyn A, Raboud J, et al. : The role of cytology (pap tests) and human papillomavirus testing in anal cancer screening. AIDS 2010;24:1307–1313 - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical