Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2016 Sep 27;17(1):197.
doi: 10.1186/s13059-016-1065-2.

Prodigious plant methylomes

Affiliations
Comment

Prodigious plant methylomes

Mary Gehring. Genome Biol. .

Abstract

Schmitz and colleagues recently investigated DNA methylation patterns in diverse flowering plant species, finding substantial variation in the extent and distribution of methylation in angiosperms.Please see related Research article: http://www.doi.org/10.1186/s13059-016-1059-0.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Generic methylation patterns in plants. Genes (dark orange boxes) are CG methylated (blue dots) but can also contain non-CG methylation (green and red dots) if TEs or TE fragments (light orange boxes) are present internally. TEs are methylated in all sequence contexts, with CHH methylation more concentrated at TE ends than internal regions in some species. Other sequence features, such as direct repeats (green arrows), are also subject to DNA methylation in all sequence contexts

Comment on

  • Widespread natural variation of DNA methylation within angiosperms.
    Niederhuth CE, Bewick AJ, Ji L, Alabady MS, Kim KD, Li Q, Rohr NA, Rambani A, Burke JM, Udall JA, Egesi C, Schmutz J, Grimwood J, Jackson SA, Springer NM, Schmitz RJ. Niederhuth CE, et al. Genome Biol. 2016 Sep 27;17(1):194. doi: 10.1186/s13059-016-1059-0. Genome Biol. 2016. PMID: 27671052 Free PMC article.

References

    1. Niederhuth CE, Bewick AJ, Ji L, Alabady M, Do Kim K, Page JT, et al. Widespread natural variation of DNA methylation in angiosperms. Genome Biol. 2016. www.doi.org/10.1186/s13059-016-1059-0. - DOI - PMC - PubMed
    1. Thomas AJ, Sherratt HS. The isolation of nucleic acid fractions from plant leaves and their purine and pyrimidine composition. Biochem J. 1956;62:1–4. doi: 10.1042/bj0620001. - DOI - PMC - PubMed
    1. Du J, Johnson LM, Jacobsen SE, Patel DJ. DNA methylation pathways and their crosstalk with histone methylation. Nat Rev Mol Cell Biol. 2015;16:519–32. doi: 10.1038/nrm4043. - DOI - PMC - PubMed
    1. Matzke MA, Mosher RA. RNA-directed DNA methylation: an epigenetic pathway of increasing complexity. Nat Rev Genet. 2014;15:394–408. doi: 10.1038/nrg3683. - DOI - PubMed
    1. Li Q, Gent JI, Zynda G, Song J, Makarevitch I, Hirsch CD, et al. RNA-directed DNA methylation enforces boundaries between heterochromatin and euchromatin in the maize genome. Proc Natl Acad Sci U S A. 2015;112:14728–33. doi: 10.1073/pnas.1514680112. - DOI - PMC - PubMed

LinkOut - more resources