Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Oct;138(4):e20151553.
doi: 10.1542/peds.2015-1553.

Neurobehavioral Disorder Associated With Prenatal Alcohol Exposure

Joseph F Hagan Jr  1 , Tatiana Balachova  2 , Jacquelyn Bertrand  3 , Ira Chasnoff  4 , Elizabeth Dang  3 , Daniel Fernandez-Baca  5 , Julie Kable  6 , Barry Kosofsky  7 , Yasmin N Senturias  8 , Natasha Singh  3 , Mark Sloane  9 , Carol Weitzman  10 , Jennifer Zubler  3 ; Neurobehavioral Disorder Associated With Prenatal Alcohol Exposure Workgroup; American Academy of Pediatrics
Affiliations

Neurobehavioral Disorder Associated With Prenatal Alcohol Exposure

Joseph F Hagan Jr et al. Pediatrics. 2016 Oct.

Abstract

Children and adolescents affected by prenatal exposure to alcohol who have brain damage that is manifested in functional impairments of neurocognition, self-regulation, and adaptive functioning may most appropriately be diagnosed with neurobehavioral disorder associated with prenatal exposure. This Special Article outlines clinical implications and guidelines for pediatric medical home clinicians to identify, diagnose, and refer children regarding neurobehavioral disorder associated with prenatal exposure. Emphasis is given to reported or observable behaviors that can be identified as part of care in pediatric medical homes, differential diagnosis, and potential comorbidities. In addition, brief guidance is provided on the management of affected children in the pediatric medical home. Finally, suggestions are given for obtaining prenatal history of in utero exposure to alcohol for the pediatric patient.

PubMed Disclaimer

Conflict of interest statement

POTENTIAL CONFLICT OF INTEREST: The authors have indicated they have no potential conflicts of interest to disclose.

Figures

FIGURE 1
FIGURE 1
FIGURE 1A. ND-PAE Age-Dependent Symptom Diagnosis Guidelines: Neurocognitive Domain. FIGURE 1B. ND-PAE Age-Dependent Symptom Diagnosis Guidelines: Self-Regulation Domain. FIGURE 1C. ND-PAE Age-Dependent Symptom Diagnosis Guidelines: Adaptive Domains.
FIGURE 1
FIGURE 1
FIGURE 1A. ND-PAE Age-Dependent Symptom Diagnosis Guidelines: Neurocognitive Domain. FIGURE 1B. ND-PAE Age-Dependent Symptom Diagnosis Guidelines: Self-Regulation Domain. FIGURE 1C. ND-PAE Age-Dependent Symptom Diagnosis Guidelines: Adaptive Domains.
FIGURE 1
FIGURE 1
FIGURE 1A. ND-PAE Age-Dependent Symptom Diagnosis Guidelines: Neurocognitive Domain. FIGURE 1B. ND-PAE Age-Dependent Symptom Diagnosis Guidelines: Self-Regulation Domain. FIGURE 1C. ND-PAE Age-Dependent Symptom Diagnosis Guidelines: Adaptive Domains.
See this image and copyright information in PMC

Comment in

References

    1. Stratton KR, Howe CJ, Battaglia FC. Fetal Alcohol Syndrome: Diagnosis, Epidemiology, Prevention, and Treatment. Washington, DC: National Academies Press; 1996.
    1. American Psychiatric Association. The Diagnostic and Statistical Manual of Mental Disorders. 5. Arlington, VA: American Psychiatric Association Publishing; 2013.
    1. Kable JA, O’Connor MJ, Olson HC, et al. Neurobehavioral disorder associated with prenatal alcohol exposure (ND-PAE): proposed DSM-5 diagnosis. Child Psychiatry Hum Dev. 2016;47(2):335–346. - PubMed
    1. Olson HC. Advancing recognition of fetal alcohol spectrum disorders: the proposed DSM-5 diagnosis of “neurobehavioral disorder associated with prenatal alcohol exposure (ND-PAE)”. Curr Dev Disord Rep. 2015;2(3):187–198.
    1. Tan CH, Denny CH, Cheal NE, Sniezek JE, Kanny D Centers for Disease Control and Prevention. Alcohol use and binge drinking among women of childbearing age: United States, 2011–2013. MMWR Morb Mortal Wkly Rep. 2015;64(37):1042–1046. - PubMed

Publication types