Commentary: Periodontal Treatment and Inflammation in Diabetes: Association or Causation?
- PMID: 27677805
- PMCID: PMC5842079
- DOI: 10.1902/jop.2016.160433
Commentary: Periodontal Treatment and Inflammation in Diabetes: Association or Causation?
Abstract
The causal effect of periodontal treatment on systemic outcomes is unclear because even randomized controlled trials (RCTs) have conflicting results. Two models are proposed to explain the apparently conflicting findings from RCTs evaluating the effect of periodontal treatment on inflammation and systemic outcomes among individuals with type 2 diabetes.
Keywords: Causality; diabetes mellitus; inflammation; obesity; periodontal disease; randomized controlled trial.
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Comment on
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Systemic Inflammatory Biomarkers and Their Association With Periodontal and Diabetes-Related Factors in the Diabetes and Periodontal Therapy Trial, A Randomized Controlled Trial.J Periodontol. 2016 Aug;87(8):900-13. doi: 10.1902/jop.2016.150727. Epub 2016 Apr 25. J Periodontol. 2016. PMID: 27108476 Clinical Trial.
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