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. 2016 Jul 19;50(3):308-12.
doi: 10.1515/raon-2016-0039. eCollection 2016 Sep 1.

Metastatic sebaceous cell carcinoma, review of the literature and use of electrochemotherapy as possible new treatment modality

Simone Ribero  1 , Eugenio Sportoletti Baduel  1 , Matteo Brizio  2 , Franco Picciotto  3 , Emi Dika  4 , Maria Teresa Fierro  2 , Giuseppe Macripò  3 , Pietro Quaglino  2
Affiliations

Metastatic sebaceous cell carcinoma, review of the literature and use of electrochemotherapy as possible new treatment modality

Simone Ribero et al. Radiol Oncol. .

Abstract

Background: Metastatic extraorbital sebaceous carcinoma is a rare event that could involve the head and neck. The treatment of choice for the initial stage of the disease is surgery and/or radiotherapy. The treatment of recurrent or advanced disease is still controversial.

Material and methods: Extensive literature search was done, and the treatment options are discussed.

Results: Results. The literature search found several treatment modalities in use for the treatment of metastatic extraorbital sebaceous carcinoma. Electrochemotherapy was not included in the reported treatments. We used this technique for a man of 85 years old with a recurrent and locally metastatic extraorbital sebaceous carcinoma of the scalp. During the period of 8 months, two sessions of electrochemotherapy were employed, which resulted in an objective response of the tumour and good quality of life.

Conclusions: Electrochemotherapy has shown to be a interesting tools for treatment of metastatic extraorbital sebaceous carcinoma when other radical options are not available or convenient.

Keywords: electrochemotherapy; extraorbital tumour; head and neck tumour; sebaceous carcinoma.

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Figures

Figure 1
Figure 1
Metastatic sebaceous carcinoma, before electrochemotherapy.
Figure 2
Figure 2
Response to treatment after two electrochemotherapy sessions (2 months).
See this image and copyright information in PMC

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