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Comment
. 2016 Sep 28;48(10):1102-3.
doi: 10.1038/ng.3687.

A saltationist theory of cancer evolution

Florian Markowetz  1
Affiliations
Comment

A saltationist theory of cancer evolution

Florian Markowetz. Nat Genet. .

Abstract

A new study based on single-nucleus sequencing reports that triple-negative breast cancers acquire copy number aberrations in short punctuated bursts in the earliest stages of tumor evolution, rather than continuously and gradually, challenging prevailing models of tumor evolution.

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References

    1. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6496-505 - PubMed
    1. Cancer Cell. 2014 Nov 10;26(5):653-67 - PubMed
    1. Nat Genet. 2016 Oct;48(10 ):1119-30 - PubMed
    1. Nat Genet. 2015 Mar;47(3):209-16 - PubMed
    1. Cell. 2011 Jan 7;144(1):27-40 - PubMed

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