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. 2013 Jul 16;24(2):61-7.
eCollection 2013 Jul.

Cystatin C in Acute Coronary Syndrome

Moushumi Lodh  1 , Ashok Parida  2 , Joy Sanyal  3 , Arunangshu Ganguly  2
Affiliations

Cystatin C in Acute Coronary Syndrome

Moushumi Lodh et al. EJIFCC. .

Abstract

Cystatin C has been regarded as a novel sensitive marker for the assessment of renal function, and the role of cystatin C as a predictor of cardiovascular events in patients with impaired renal function has been confirmed in clinical studies. In this study we assessed the association between cystatin C and Coronary artery disease [CAD] in a consecutive series of patients with normal kidney function in order to avoid the well-known effect of overt renal insufficiency on coronary atherosclerosis, and evaluate whether cystatin C has an ability to identify individuals at a higher risk for CAD among patients belonging to a low-risk category according to estimated glomerular filtration rate .The current study and review of literature demonstrated that serum levels of cystatin C, were independently associated with the development of CAD.

Keywords: ACS; Biomarkers; Coronary artery disease; Cystatin C; HsCRP; cysteine protease.

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Figures

Figure 1
Figure 1
Scatter diagram to show correlation of Cystatin C and creatinine levels in acute coronary syndrome.
Figure 2
Figure 2
Scatter diagram to show the correlation of cystatin C with HsCRP levels in Acute coronary syndrome.
Figure 3
Figure 3
ROC Curve showing Sensitivity and Specificity of Cystatin C in ACS.
See this image and copyright information in PMC

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