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Review
. 2016 Sep 18;37(5):263-9.
doi: 10.13918/j.issn.2095-8137.2016.5.263.

Lamprey: a model for vertebrate evolutionary research

Yang Xu  1 , Si-Wei Zhu  1 , Qing-Wei Li  2
Affiliations
Review

Lamprey: a model for vertebrate evolutionary research

Yang Xu et al. Zool Res. .

Abstract

Lampreys belong to the superclass Cyclostomata and represent the most ancient group of vertebrates. Existing for over 360 million years, they are known as living fossils due to their many evolutionally conserved features. They are not only a keystone species for studying the origin and evolution of vertebrates, but also one of the best models for researching vertebrate embryonic development and organ differentiation. From the perspective of genetic information, the lamprey genome remains primitive compared with that of other higher vertebrates, and possesses abundant functional genes. Through scientific and technological progress, scientists have conducted in-depth studies on the nervous, endocrine, and immune systems of lampreys. Such research has significance for understanding and revealing the origin and evolution of vertebrates, and could contribute to a greater understanding of human diseases and treatments. This review presents the current progress and significance of lamprey research.

Keywords: Endocrine; Functional gene; Immune; Lamprey; Nerve.

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Figures

Figure 1
Figure 1
Phylogeny of select Chordate taxa
Figure 2
Figure 2
Rearrangement of antigen receptors of lampreys
Figure 3
Figure 3
Location of immune body, oral gland and gill cage of lamprey
See this image and copyright information in PMC

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