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. 2017 Mar;31(6):660-666.
doi: 10.1080/14786419.2016.1219861. Epub 2016 Aug 12.

Chemical constituents and antitumor activity from Paris polyphylla Smith var. yunnanensis

Songsong Jing  1 , Ying Wang  2 , Xia Li  1 , Shuli Man  3 , Wenyuan Gao  1
Affiliations

Chemical constituents and antitumor activity from Paris polyphylla Smith var. yunnanensis

Songsong Jing et al. Nat Prod Res. 2017 Mar.

Abstract

Eleven compounds were isolated from the rhizomes of Paris polyphylla Smith var. yunnanensis. Their structures were elucidated on the basis of rigorous 1D and 2D NMR experiments as well as comparison with the literature data. To the best of our knowledge, compound 1 was only predicted by UPLC/Q-TOF MSE and the NMR spectroscopic data was given for the first time. The cytotoxic activities of all compounds on mouse B16 cells were evaluated. Among the tested molecules, compounds 6-9 showed strong cytotoxicities, while compound 1 did not show significant effect.

Keywords: Liliaceae; Paris polyphylla Smith var. yunnanensis; antitumor activity; steroidal saponins.

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