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. 2017 Jul;22(3):413-428.
doi: 10.1177/2156587216669628. Epub 2016 Sep 30.

Clinical Effects of Krachaidum ( Kaempferia parviflora): A Systematic Review

Surasak Saokaew  1   2   3 , Preyanate Wilairat  1 , Paranya Raktanyakan  1 , Piyameth Dilokthornsakul  3 , Teerapon Dhippayom  3 , Chuenjid Kongkaew  3 , Rosarin Sruamsiri  3 , Anchalee Chuthaputti  4 , Nathorn Chaiyakunapruk  2   3   5   6
Affiliations

Clinical Effects of Krachaidum ( Kaempferia parviflora): A Systematic Review

Surasak Saokaew et al. J Evid Based Complementary Altern Med. 2017 Jul.

Abstract

Kaempferia parviflora (Krachaidum) is a medicinal plant in the family Zingiberaceae. Its rhizome has been used as folk medicine for many centuries. A number of pharmacological studies of Krachaidum had claimed benefits for various ailments. Therefore, this study aimed to systematically search and summarize the clinical evidences of Krachaidum in all identified indications. Of 683 records identified, 7 studies were included. From current clinical trials, Krachaidum showed positive benefits but remained inconclusive since small studies were included. Even though results found that Krachaidum significantly increased hand grip strength and enhanced sexual erotic stimuli, these were based on only 2 studies and 1 study, respectively. With regard to harmful effects, we found no adverse events reported even when Krachaidum 1.35 g/day was used. Therefore, future studies of Krachaidum are needed with regards to both safety and efficacy outcomes.

Keywords: Kaempferia parviflora; complementary and alternative medicine; systematic review.

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Conflict of interest statement

Declaration of Conflicting Interests: The authors declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: AC is currently a government official under the Department for Development of Thai Traditional and Alternative Medicine, Ministry of Public Health, Nonthaburi, Thailand. The other authors have no potential conflicts of interest.

Figures

Figure 1.
Figure 1.
Flow diagram of selected articles.
Figure 2.
Figure 2.
Risk of bias: (A) Risk of bias in each study; (B) Summary risk of bias of included studies.
Figure 3.
Figure 3.
Forest plot illustrating the effect of Krachaidum on hand grip strength.
See this image and copyright information in PMC

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