Complementary peptide sequences in partner proteins of the adenovirus capsid

Abstract

Peptides quite similar to the signal peptide of secretory proteins were found in adenovirus serotype 2 fibre. This was surprising because this protein does not have this property. Because the N-end fibre is implicated in the penton base-fibre interaction and complementary peptides to the N-sequence fibre were found in penton base protein, these complementary peptides might be involved in the protein-protein recognition and interaction process. So far, known structural data agree with such an hypothesis.