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Review
. 2016 Oct;42(7):789-797.
doi: 10.1055/s-0036-1592304. Epub 2016 Oct 5.

Direct Oral Anticoagulants and Women

Hannah Cohen  1 , Deepa R J Arachchillage  2 , Jan Beyer-Westendorf  3 , Saskia Middeldorp  4 , Rezan A Kadir  5
Affiliations
Review

Direct Oral Anticoagulants and Women

Hannah Cohen et al. Semin Thromb Hemost. 2016 Oct.

Abstract

Direct oral anticoagulants (DOACs) provide an effective, safe, and convenient therapeutic alternative to warfarin and other vitamin K antagonists (VKAs), and are now established for a wide range of indications. The use of DOACs in women merits special consideration due to two main situations: first, in relation to fertility, pregnancy, and lactation in women of reproductive age; second, because of their bleeding risk, leading to abnormal uterine and/or other genital tract bleeding. This review focuses on these two clinical situations, including approaches to management in the context of available information.

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