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Review
. 2017 Jan;23(1):86-95.
doi: 10.1002/lt.24646.

Global lessons in graft type and pediatric liver allocation: A path toward improving outcomes and eliminating wait-list mortality

Evelyn K Hsu  1 , George V Mazariegos  2
Affiliations
Review

Global lessons in graft type and pediatric liver allocation: A path toward improving outcomes and eliminating wait-list mortality

Evelyn K Hsu et al. Liver Transpl. 2017 Jan.

Abstract

Current literature and policy in pediatric liver allocation and organ procurement are reviewed here in narrative fashion, highlighting historical context, ethical framework, technical/procurement considerations, and support for a logical way forward to an equitable pediatric liver allocation system that will improve pediatric wait-list and posttransplant outcomes without adversely affecting adults. Where available, varying examples of successful international pediatric liver allocation and split-liver policy will be compared to current US policy to highlight potential strategies that can be considered globally. Liver Transplantation 23:86-95 2017 AASLD.

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Figures

Figure 1
Figure 1
Pretransplant mortality rates among pediatric liver transplant candidates. From Kim et al.1 (2016).
Figure 2
Figure 2
Split liver algorithm with pediatric prioritization and incentivized splitting (Hong et al.14 [2009]).
See this image and copyright information in PMC

References

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