Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Oct 3;16(1):107.
doi: 10.1186/s12903-016-0300-2.

Prevalence of oral manifestations in children and adolescents with cancer submitted to chemotherapy

Affiliations

Prevalence of oral manifestations in children and adolescents with cancer submitted to chemotherapy

Deise Berger Velten et al. BMC Oral Health. .

Abstract

Background: Oral complications may be observed during chemotherapy and are important side effects that may directly affect the anticancer treatment, even causing septicaemia in some cases. This research was done in order to evaluate changes in oral lesions during follow-up of children and adolescents in chemotherapy at Hospital Estadual Infantil Nossa Senhora da Glória (HEINSG).

Methods: The study design was longitudinal, 45 patients were evaluated and monitored for 1 month after the initiation of chemotherapy. Twenty-eight patients were male and 17 female, ranging from 3 months to 18 years old.

Results: The results show an increase in the number of mucositis cases and a decrease in xerostomia cases after the initiation of treatment, and other oral lesions were also found in low numbers.

Conclusions: It is possible to avoid oral complications by maintaining a good oral health, and reducing infectious outbreaks. It is also feasible to obtain an early diagnosis of, and treat these oral complications, preventing them from following a more severe clinical course that may negatively affect the individual's treatment. This outcome requires the presence of a dental surgeon on the multidisciplinary cancer treatment team.

Keywords: Chemotherapy; Oncology; Oral manifestations.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Deaths during the monitoring of patients at HEINSG

References

    1. Ministério da Saúde, Secretaria Nacional de Assistência à Saúde, Instituto Nacional do Câncer . Estimativa 2010: incidência do câncer no Brasil. Rio de Janeiro: INCA; 2009.
    1. Instituto Nacional do Câncer. Estimativa/2012: incidência do câncer no Brasil. Rio de Janeiro: INCA; 2011. Disponível em: http://portal.saude.sp.gov.br/resources/ses/perfil/gestor/homepage/estim.... Acessado 23 set 2012.
    1. Instituto Nacional do Câncer. Estimativa/2014: incidência do câncer no Brasil. Rio de Janeiro: INCA; 2014. Disponível em: http://www.saude.sp.gov.br/resources/ses/perfil/gestor/homepage/outros-d.... Acessado 20 abr 2014.
    1. Braga PE, Latorre MRDO, Curado MP. Câncer na infância: análise comparativa da incidência, mortalidade e sobrevida em Goiânia (Brasil) e outros países. Cad Saude Publica. 2002;18(1):33–44. doi: 10.1590/S0102-311X2002000100004. - DOI - PubMed
    1. Cheng KKF, Molassiotis A, Chang AM, Wai WC, Cheung SS. Evaluation of an oral care protocol intervention in the prevention of chemotherapy-induced oral mucositis in paediatric cancer patients. Eur J Cancer. 2001;37:2056–2063. doi: 10.1016/S0959-8049(01)00098-3. - DOI - PubMed

Substances

LinkOut - more resources