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. 2016 Oct 6;64(1):5-6.
doi: 10.1016/j.molcel.2016.09.022.

Mitochondrial Diseases: Shortcuts to Therapies and Therapeutic Shortcuts

Michael P Murphy  1
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Mitochondrial Diseases: Shortcuts to Therapies and Therapeutic Shortcuts

Michael P Murphy. Mol Cell. .
Free article

Abstract

In this issue of Molecular Cell, Barrow et al. (2016) use two complementary approaches-one an assessment of a chemical library, and the other a genome-wide CRISPR screen-that both identify bromodomain-containing protein 4 (Brd4) as a therapeutic target for mtDNA diseases affecting complex I.

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