Review
doi: 10.1016/j.cell.2016.09.036.
Remembering the Past: A New Form of Protein-Based Inheritance
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- PMID: 27716500
- DOI: 10.1016/j.cell.2016.09.036
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Review
Remembering the Past: A New Form of Protein-Based Inheritance
Cell.
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Free article
Abstract
A comprehensive analysis uncovered a set of yeast proteins promoting protein-based inheritance that shares many of the non-Mendelian properties of prions. Lacking any sequence or structural signatures of known prions, these proteins represent a new class of non-amyloid, protein-based epigenetic determinants that can control phenotype without impacting genotype.
Copyright © 2016 Elsevier Inc. All rights reserved.
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