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. 2016 Oct 6;19(4):421-422.
doi: 10.1016/j.stem.2016.09.009.

Out of Many, One: Computational Reconstruction of Mouse Skin using Single-Cell Transcriptomics

James C Chen  1 , Angela M Christiano  2
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Out of Many, One: Computational Reconstruction of Mouse Skin using Single-Cell Transcriptomics

James C Chen et al. Cell Stem Cell. .
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Abstract

Mammalian skin is a complex and heterogeneous tissue with several distinct compartments and stem cell populations. Joost et al. (2016) now use single-cell RNaseq to comprehensively reconstruct this complexity, revealing spatial and pseudotemporal differences between transcriptional programs in distinct compartments and a common basal program in skin stem cell populations.

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