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. 1989 Jun;41(6):334-43.

[Cerebrospinal fluid parameters in Guillain-Barré polyradiculitis. Importance of barrier disorder and intrathecal immunoglobulin synthesis]

[Article in German]
R Papen  1 , K Warecka
Affiliations
  • PMID: 2772069

[Cerebrospinal fluid parameters in Guillain-Barré polyradiculitis. Importance of barrier disorder and intrathecal immunoglobulin synthesis]

[Article in German]
R Papen et al. Psychiatr Neurol Med Psychol (Leipz). 1989 Jun.

Abstract

With routine CSF determination of 21 patients with GBS the BBB and the intrathecal IgG synthesis was investigated when calculated CSF/serum albumin ratio and CSF IgG-index respectively. Only in 2 of 21 patients (9.5%) an intrathecal IgG synthesis and in 14 of 21 patients (67%) a BBB damage was found. The BBB was considered as an important pathogenetic factor in GBS. A hypothesis for the development of the albumino-cytological dissociation is presented.

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