Eyes on systems pharmacology

Affiliations

¹ Yueyang Hospital & Clinical Research Institute of Integrative Medicine, Shanghai University of TCM, Shanghai 200437, China. Electronic address: chenyu6639@hotmail.com.
² Department of Pharmacology, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA; Department of Medicine, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA; Veterans Administration Medical Center, Cleveland, OH 44106, USA. Electronic address: tsk@case.edu.
³ Department of Pharmacology, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA; Veterans Administration Medical Center, Cleveland, OH 44106, USA. Electronic address: pdk7@case.edu.
⁴ Department of Pharmacology, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA. Electronic address: kxp65@case.edu.

Editorial

Yu Chen et al. Pharmacol Res. 2016 Dec.

. 2016 Dec:114:39-41.

doi: 10.1016/j.phrs.2016.09.026. Epub 2016 Oct 5.

¹ Yueyang Hospital & Clinical Research Institute of Integrative Medicine, Shanghai University of TCM, Shanghai 200437, China. Electronic address: chenyu6639@hotmail.com.
² Department of Pharmacology, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA; Department of Medicine, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA; Veterans Administration Medical Center, Cleveland, OH 44106, USA. Electronic address: tsk@case.edu.
³ Department of Pharmacology, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA; Veterans Administration Medical Center, Cleveland, OH 44106, USA. Electronic address: pdk7@case.edu.
⁴ Department of Pharmacology, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA. Electronic address: kxp65@case.edu.

No abstract available

Figures

1. Hunter DJ. Gene-environment interactions in human diseases. Nat. Rev. Genet. 2005;6(4):287–298. - PubMed
1. Chen Y, Palczewski K. Systems pharmacology links GPCRs with retinal degenerative disorders. Annu. Rev. Pharmacol. Toxicol. 2016;56:273–298. http://dx.doi.org/10.1146/annurev-pharmtox-010715-103033, Epub 2015 Mar 23. - DOI - PMC - PubMed
1. Iyengar R. Complex diseases require complex therapies. EMBO Rep. 2013;14(12):1039–1042. http://dx.doi.org/10.1038/embor.2013.177, Epub 2013 Nov 15. - DOI - PMC - PubMed
1. Chen Y, Okano K, Maeda T, Chauhan V, Golczak M, Maeda A, Palczewski K. Mechanism of all-trans-retinal toxicity with implications for stargardt disease and age-related macular degeneration. J. Biol. Chem. 2012;287(7):5059–5069. http://dx.doi.org/10.1074/jbc.M111.315432, Epub 2011 Dec 19. - DOI - PMC - PubMed
1. Chen Y, Palczewska G, Mustafi D, Golczak M, Dong Z, Sawada O, Maeda T, Maeda A, Palczewski K. Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration. J. Clin. Invest. 2013;123(12):5119–5134. http://dx.doi.org/10.1172/JCI69076, Epub 2013 Nov 15. - DOI - PMC - PubMed