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Review
. 2016:2016:4971572.
doi: 10.1155/2016/4971572. Epub 2016 Sep 19.

Applications of Anterior Segment Optical Coherence Tomography in Cornea and Ocular Surface Diseases

Sang Beom Han  1 , Yu-Chi Liu  2 , Karim Mohamed Noriega  3 , Jodhbir S Mehta  2
Affiliations
Review

Applications of Anterior Segment Optical Coherence Tomography in Cornea and Ocular Surface Diseases

Sang Beom Han et al. J Ophthalmol. 2016.

Abstract

Optical coherence tomography (OCT) is a noncontact technology that produces high-resolution cross-sectional images of ocular tissues. Anterior segment OCT (AS-OCT) enables the precise visualization of anterior segment structure; thus, it can be used in various corneal and ocular surface disorders. In this review, the authors will discuss the application of AS-OCT for diagnosis and management of various corneal and ocular surface disorders. Use of AS-OCT for anterior segment surgery and postoperative management will also be discussed. In addition, application of the device for research using human data and animal models will be introduced.

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Conflict of interest statement

None of the authors have proprietary interests in the study or financial interests to disclose.

Figures

Figure 1
Figure 1
An AS-OCT image of a patient with granular dystrophy. AS-OCT can accurately show the location and depth of the visually significant stromal haze.
Figure 2
Figure 2
A TD AS-OCT image demonstrating localized Descemet's membrane detachment (white arrow) adjacent to the wound and internal wound gaping (black arrow) that was not detected in slit-lamp examination.
Figure 3
Figure 3
An AS-OCT image of precut donor cornea for Descemet's stripping automated endothelial keratoplasty (DSAEK) taken for evaluation of thickness of graft donor tissue.
Figure 4
Figure 4
An intraoperative AS-OCT image taken during deep anterior lamellar keratoplasty (DALK) that confirms an optimal descemetic or predescemetic dissection.
Figure 5
Figure 5
AS-OCT images demonstrating detachment of the Descemet's membrane (DM; white arrow) after DALK (a) and reattachment of the DM after intracameral air injection (b).
Figure 6
Figure 6
An AS-OCT image demonstrating anterior chamber inflammation in a rejected graft in a rat model.
See this image and copyright information in PMC

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