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. 2016 Oct 13;52(84):12454-12457.
doi: 10.1039/c6cc07110d.

Studies of G-quadruplexes formed within self-assembled DNA mini-circles

Beata Klejevskaja  1 , Alice L B Pyne  2 , Matthew Reynolds  3 , Arun Shivalingam  3 , Richard Thorogate  2 , Bart W Hoogenboom  4 , Liming Ying  5 , Ramon Vilar  1
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Free article

Studies of G-quadruplexes formed within self-assembled DNA mini-circles

Beata Klejevskaja et al. Chem Commun (Camb). .
Free article

Abstract

We have developed self-assembled DNA mini-circles that contain a G-quadruplex-forming sequence from the c-Myc oncogene promoter and demonstrate by FRET that the G-quadruplex unfolding kinetics are 10-fold slower than for the simpler 24-mer G-quadruplex that is commonly used for FRET experiments.

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