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. 1989 Apr-Jun;19(2):165-72.
doi: 10.1007/BF02871805.

Cholesterol distribution between HDL subfractions. A study of 498 subjects

D Sommariva  1 , A Branchi, D Bonfiglioli, M Tirrito, E Cabrini, C Pini, L Scandiani, A Rovellini, A Fasoli
Affiliations

Cholesterol distribution between HDL subfractions. A study of 498 subjects

D Sommariva et al. Ric Clin Lab. 1989 Apr-Jun.

Abstract

In 498 subjects (205 normolipidemics and 293 hyperlipidemics) of both sexes, the cholesterol content of high density lipoprotein (HDL) subfractions has been determined. The serum concentration of total HDL-cholesterol appears to be more strictly related to the cholesterol content of HDL2 than to that of HDL3. This latter one, however, gives a contribution to the variability of HDL-cholesterol so that the value of HDL-cholesterol cannot be assumed as a reliable estimate of the serum level of the more anti-atherogenic HDL2 subfraction. The cholesterol content of HDL and its subfractions is higher in women than in men and decreases with increasing serum VLDL-cholesterol level and body weight. Both HDL2- and HDL3-cholesterol appear to largely depend from the metabolism of triglyceride-rich lipoproteins in accordance with the data of experimental studies.

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