The role of postoperative chemoradiation for oropharynx carcinoma: A critical appraisal revisited
- PMID: 27727449
- PMCID: PMC5161595
- DOI: 10.1002/cncr.30266
The role of postoperative chemoradiation for oropharynx carcinoma: A critical appraisal revisited
Abstract
A recent review in this Journal, which criticizes NCCN’s recommendations based, in part, on the RTOG 9501 and the EORTC 22931 trials, warrants comment. We herein provide additional data addressing many of the points and misinterpretations raised in that review which convincingly supports the use of concomitant chemotherapy and radiotherapy in patients with good performance status and high-risk pathologic features after surgery for mucosal head and neck squamous cell carcinoma.
Conflict of interest statement
There are no conflicts of interest disclosures from any of the authors.
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Comment in
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The role of postoperative chemoradiation for oropharyngeal carcinoma: A critical appraisal revisited.Cancer. 2017 Mar 1;123(5):887-888. doi: 10.1002/cncr.30480. Epub 2016 Dec 20. Cancer. 2017. PMID: 27997985 No abstract available.
Comment on
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Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck.N Engl J Med. 2004 May 6;350(19):1937-44. doi: 10.1056/NEJMoa032646. N Engl J Med. 2004. PMID: 15128893 Clinical Trial.
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The role of postoperative chemoradiation for oropharynx carcinoma: a critical appraisal of the published literature and National Comprehensive Cancer Network guidelines.Cancer. 2015 Jun 1;121(11):1747-54. doi: 10.1002/cncr.29242. Epub 2015 Jan 14. Cancer. 2015. PMID: 25588360 Review.
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