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Comment
. 2016 Oct 10;39(1):1-2.
doi: 10.1016/j.devcel.2016.09.025.

A TRIM16-Galactin3 Complex Mediates Autophagy of Damaged Endomembranes

Milana Fraiberg  1 , Zvulun Elazar  2
Affiliations
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A TRIM16-Galactin3 Complex Mediates Autophagy of Damaged Endomembranes

Milana Fraiberg et al. Dev Cell. .

Abstract

Selective autophagy, an essential process for maintaining intracellular homeostasis, depends on precise target recognition and local activation. Reporting in Developmental Cell, Chauhan et al. (2016) elegantly demonstrate that interaction between TRIM16 and Galectin3 orchestrates the recruitment of core autophagic factors and activates selective autophagy at the site of damaged endomembranes.

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