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. 2016 Oct 12;16(1):304.
doi: 10.1186/s12884-016-1096-4.

Pregnancy in patients with tuberculosis: a TBNET cross-sectional survey

Graham H Bothamley  1 , Cordula Ehlers  2 , Irina Salonka  3 , Alena Skrahina  3 , Angels Orcau  4 , Luigi R Codecasa  5 , Maurizio Ferrarese  5 , Dragica Pesut  6 , Ivan Solovic  7 , Andrii Dudnyk  8 , Luis Anibarro  9 , Claudia Denkinger  10 , Lorenzo Guglielmetti  11 , Inge Muylle  12 , Marco Confalonieri  13
Affiliations

Pregnancy in patients with tuberculosis: a TBNET cross-sectional survey

Graham H Bothamley et al. BMC Pregnancy Childbirth. .

Abstract

Background: Objectives: To determine whether the incidence of tuberculosis with pregnancy is more common than would be expected from the crude birth rate; to see whether there is significant delay in the diagnosis of tuberculosis during pregnancy.

Method: Design: A cross-sectional survey.

Setting: 13 tuberculosis clinics within different European countries and the USA.

Population/sample: All patients with tuberculosis seen at these clinics for a period > 1 year.

Instrument: Questionnaire survey based on continuous data collection.

Main outcome measures: number and proportion of women with tuberculosis who were pregnant; timing of diagnosis in relation to pregnancy, including those who were pregnant or delivered in the 3 months prior to the diagnosis of TB and those who developed TB within 3 months after delivery.

Results: Pregnancy occurred in 224 (1.5 %) of 15,217 TB patients and followed the expected rate predicted from the crude birth rate for the clinic populations. TB was diagnosed more commonly in the 3 months after delivery (n = 103) than during pregnancy (n = 68; χ 2 = 25.1, P < 0.001).

Conclusions: TB is diagnosed more frequently after delivery, despite variations in local TB incidence and healthcare systems.

Keywords: Diagnosis; Postpartum; Pregnancy; TBNET; Tuberculosis.

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Figures

Fig. 1
Fig. 1
Flow chart of data collection
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