Electrophysiological and phonological change detection measures of auditory word processing in normal Persian-speaking children

Abstract

Objective: Auditory phoneme discrimination is a basic and important prerequisite for acquiring speech, reading, and spelling skills. Children, who are unable to perceive auditory phoneme discrimination, cannot develop phonemic representations. Therefore, the early identification of these deficits and application of effective therapeutic approaches is a necessity. We need to assess appropriately word or sound discrimination in normal populations using an objective passive task such as mismatch negativity (MMN). Therefore, the aim of the present study was to investigate MMN responses using speech stimuli (words) in 6-7 year-old normal Persian-speaking children.

Methods: Ten right-handed Persian-speaking children with normal visual and auditory acuity, aged from 6 to 7 years, participated in the study. Recording of electroencephalography (EEG) was done by 64 A g/AgCl electrodes. A new auditory paradigm was used with three deviant stimuli (/gam/,/jam/, and/tam/) which differed in the first consonant from a repeated standard word (/dam/). A total of 1500 stimuli, 750 standards and 750 deviants (250 each deviant), were presented by Cogent 2000 running in MATLAB software using two loud speakers.

Results: MMN peaked over the fronto-central sites at around 380-424 ms after the onset of the stimulus. The comparison of the MMN amplitudes elicited by three deviants revealed a significant "initial phoneme type" effect in Fz and Cz (p < 0.05). This negativity was found to be larger for manner and voicing deviants compared with that of the place of articulation (p < 0.001) on midline scalps. The comparison of the MMN latencies revealed no significant main effect of all variables (p > 0.05). Also, the results revealed that only the MMN amplitude for the/gam/deviant correlated with the percentage of correct responses (R = -0.86, p < 0.01).

Conclusion: The current study showed that words can elicit MMN responses in ∼200 ms after the onset of changes. We can objectively evaluate children's neural speech sound discrimination using the developed paradigm in a natural word context. This paradigm can be useful objectively for investigating distinctive features of sounds and phonological discrimination development in normal children.

Keywords: Children; Event-related potential (ERP); Language; Mismatch negativity (MMN); Speech discrimination.