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. 1989 May;14(5):165-7.
doi: 10.1016/0968-0004(89)90266-1.

How 'hidden' reading frames are expressed

R Cattaneo

How 'hidden' reading frames are expressed

R Cattaneo. Trends Biochem Sci. 1989 May.

Abstract

Secondary reading frames, 'hidden' under other reading frames, are used for coordinated expression of proteins in several eukaryotic viruses. In some genes, ribosomal frameshifting and initiation or reinitiation of protein synthesis on internal AUG codons are translational mechanisms allowing access to such 'hidden' reading frames. In others, secondary reading frames are translated from alternatively spliced or edited mRNAs.

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References

    1. Bos J.L., Polder L.J., Bernards R., Schrier P.I., van den Ellen P.J., van der Eb A.J., Ormondt H. Cell. 1981;27:121–131. - PubMed
    1. Shaw M.W., Choppin P.W., Lamb R.A. Vol. 80. 1983. pp. 4879–4883. (Proc. Natl Acad. Sci. USA). - PMC - PubMed
    1. Giorgi C., Blumberg B.M., Kolakofsky D. Cell. 1983;35:829–836. - PubMed
    1. Kozak M. Cell. 1986;47:481–483. - PubMed
    1. Jacks T., Varmus H.E. Science. 1985;230:1237–1242. - PubMed

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