Not just leukemia: CMV may protect against lymphoma recurrence after allogeneic transplant

Affiliations

Comment

Jonathan U Peled et al. Leuk Lymphoma. 2017 Apr.

. 2017 Apr;58(4):759-761.

doi: 10.1080/10428194.2016.1239265. Epub 2016 Oct 12.

¹ a Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center , New York , NY , USA.

No abstract available

Comment on

Early human cytomegalovirus replication after transplantation is associated with a decreased relapse risk: evidence for a putative virus-versus-leukemia effect in acute myeloid leukemia patients.
Elmaagacli AH, Steckel NK, Koldehoff M, Hegerfeldt Y, Trenschel R, Ditschkowski M, Christoph S, Gromke T, Kordelas L, Ottinger HD, Ross RS, Horn PA, Schnittger S, Beelen DW. Elmaagacli AH, et al. Blood. 2011 Aug 4;118(5):1402-12. doi: 10.1182/blood-2010-08-304121. Epub 2011 May 3. Blood. 2011. PMID: 21540462

1. Pasquini M, Zhu X. Current uses and outcomes of hematopoietic stem cell transplantation: CIBMTR Summary Slides, 2015. [Accessed 2016];2015 < http://www.cibmtr.org>.
1. Lonnqvist B, Ringden O, Ljungman P, Wahren B, Gahrton G. Reduced risk of recurrent leukaemia in bone marrow transplant recipients after cytomegalovirus infection. Br J Haematol. 1986;63:671–679. - PubMed
1. Behrendt CE, Rosenthal J, Bolotin E, Nakamura R, Zaia J, Forman SJ. Donor and recipient CMV serostatus and outcome of pediatric allogeneic HSCT for acute leukemia in the era of CMV-preemptive therapy. Biol Blood Marrow Transplant. 2009;15:54–60. - PMC - PubMed
1. Nachbaur D, Clausen J, Kircher B. Donor cytomegalovirus seropositivity and the risk of leukemic relapse after reduced-intensity transplants. Eur J Haematol. 2006;76:414–419. - PubMed
1. Elmaagacli AH, Steckel NK, Koldehoff M, et al. Early human cytomegalovirus replication after transplantation is associated with a decreased relapse risk: evidence for a putative virus-versus-leukemia effect in acute myeloid leukemia patients. Blood. 2011;118:1402–1412. - PubMed