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. 2016 Dec;6(1):37.
doi: 10.1186/s12348-016-0107-y. Epub 2016 Oct 12.

Refractory necrotizing scleritis successfully treated with adalimumab

Lola E Lawuyi  1 , Avinash Gurbaxani  2
Affiliations

Refractory necrotizing scleritis successfully treated with adalimumab

Lola E Lawuyi et al. J Ophthalmic Inflamm Infect. 2016 Dec.

Abstract

Necrotizing scleritis is the most severe and destructive form of scleritis with vision-threatening sequelae. It is divided into with inflammation and without inflammation (scleromalacia perforans). Adalimumab is a tumour necrosis factor (TNF)-inhibiting anti-inflammatory medication licensed for the treatment of rheumatoid and psoriatic arthritis, ankylosing spondylitis and inflammatory bowel disease (in the USA). We report two cases of necrotizing scleritis successfully treated with adalimumab.

Keywords: Adalimumab; Necrotizing scleritis; TNF inhibitors.

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Figures

Fig. 1
Fig. 1
Scleral necrosis RE
Fig. 2
Fig. 2
Scleral necrosis LE
Fig. 3
Fig. 3
Resolution/control on adalimumab at 6-month follow-up
See this image and copyright information in PMC

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