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Comment
. 2016 Oct 12;20(4):407-408.
doi: 10.1016/j.chom.2016.09.009.

IFITMs: Important Factors In Trans-Mission of HIV-1

Daniel Sauter  1 , Frank Kirchhoff  2
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Comment

IFITMs: Important Factors In Trans-Mission of HIV-1

Daniel Sauter et al. Cell Host Microbe. .
Free article

Abstract

IFITMs inhibit various enveloped viral pathogens in vitro, but their relevance in vivo has remained unclear. In this issue of Cell Host & Microbe, Foster et al. (2016) show that IFITMs constitute a barrier to HIV-1 transmission and that escape from adaptive immune responses increases viral sensitivity to IFITM restriction.

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