A Commensal Protozoan Strikes a Balance in the Gut
- PMID: 27736641
- DOI: 10.1016/j.chom.2016.09.016
A Commensal Protozoan Strikes a Balance in the Gut
Abstract
Gut commensals profoundly affect host immunity and intestinal homeostasis, but the impact of commensal eukaryotic protozoans is poorly understood. In a recent Cell paper, Chudnovskiy et al. (2016) identify a commensal protozoan, Tritrichomonas musculis, that can enhance anti-bacterial defenses, but at the cost of increasing intestinal inflammation.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.Cell. 2016 Oct 6;167(2):444-456.e14. doi: 10.1016/j.cell.2016.08.076. Cell. 2016. PMID: 27716507 Free PMC article.
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