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Review
. 2016 May-Jun;31(3):252-255.
doi: 10.5935/1678-9741.20160026.

Fungal Endocarditis

Shi-Min Yuan  1
Affiliations
Review

Fungal Endocarditis

Shi-Min Yuan. Braz J Cardiovasc Surg. 2016 May-Jun.

Abstract

Fungal endocarditis is a rare and fatal condition. The Candida and Aspergillus species are the two most common etiologic fungi found responsible for fungal endocarditis. Fever and changing heart murmur are the most common clinical manifestations. Some patients may have a fever of unknown origin as the onset symptom. The diagnosis of fungal endocarditis is challenging, and diagnosis of prosthetic valve fungal endocarditis is extremely difficult. The optimum antifungal therapy still remains debatable. Treating Candida endocarditis can be difficult because the Candida species can form biofilms on native and prosthetic heart valves. Combined treatment appears superior to monotherapy. Combination of antifungal therapy and surgical debridement might bring about better prognosis.

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Conflict of interest statement

No conflict of interest.

Figures

Fig.1
Fig.1
Management protocol for fungal endocarditis based on the data summarized by Seelig et al.[32]. FE=fungal endocarditis; MIC=minimum inhibitory concentration; pt=patients
See this image and copyright information in PMC

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