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Review
. 2017 Jan 12;60(1):89-99.
doi: 10.1021/acs.jmedchem.6b01123. Epub 2016 Oct 14.

Fragment-to-Lead Medicinal Chemistry Publications in 2015

Christopher N Johnson  1 , Daniel A Erlanson  2 , Christopher W Murray  1 , David C Rees  1
Affiliations
Review

Fragment-to-Lead Medicinal Chemistry Publications in 2015

Christopher N Johnson et al. J Med Chem. .

Abstract

Fragment-based drug discovery (FBDD) is now well-established as a technology for generating new chemical leads and drugs. This Miniperspective provides a tabulated overview of the fragment-to-lead literature published in the year 2015, together with a commentary on trends observed across the FBDD field during this time. It is hoped that this tabulated summary will provide a useful point of reference for both FBDD practitioners and the wider medicinal chemistry community.

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