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. 2016 Nov 1;63(suppl 3):S61-S62.
doi: 10.1093/cid/ciw481.

Harnessing Novel Quantitative Pharmacology Approaches to Optimize the Treatment of Children With Tuberculosis

James A Seddon  1 , Mamodikoe K Makhene  2
Affiliations

Harnessing Novel Quantitative Pharmacology Approaches to Optimize the Treatment of Children With Tuberculosis

James A Seddon et al. Clin Infect Dis. .
No abstract available

Keywords: children; hollow fiber; pharmacokinetics; resistant; tuberculosis.

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Comment in

  • Old Antibiotics for Tuberculosis.
    Raoult D. Raoult D. Clin Infect Dis. 2017 Apr 1;64(7):983. doi: 10.1093/cid/cix037. Clin Infect Dis. 2017. PMID: 28362942 No abstract available.
  • Reply to Raoult.
    Seddon JA, Makhene MK, Gumbo T. Seddon JA, et al. Clin Infect Dis. 2017 Apr 1;64(7):984. doi: 10.1093/cid/cix038. Clin Infect Dis. 2017. PMID: 28362943 Free PMC article. No abstract available.

References

    1. World Health Organization. Global tuberculosis report. Geneva, Switzerland: WHO, 2015.
    1. Dodd PJ, Gardiner E, Coghlan R, Seddon JA. Burden of childhood tuberculosis in 22 high-burden countries: a mathematical modelling study. Lancet Global Health 2014; 2:e453–9. - PubMed
    1. Marais BJ, Gie RP, Schaaf HS et al. . The natural history of childhood intra-thoracic tuberculosis: a critical review of literature from the pre-chemotherapy era. Int J Tuberc Lung Dis 2004; 8:392–402. - PubMed
    1. World Health Organization. Rapid advice. Treatment of tuberculosis in children. WHO/HTM/TB/2010.13 Geneva, Switzerland: WHO, 2010. - PubMed
    1. Swaminathan S, Pasipanodya JG, Ramachandran G, et al Drug concentration thresholds predictive of therapy failure and death in children with tuberculosis: bread crumb trails in random forests. Clin Infect Dis 2016; 63(suppl 3):S63–74. - PMC - PubMed

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