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. 1978 Jan-Feb;27(1):1-10.

Influence of age and cortisone treatment on two intestinal lysosomal hydrolases in young rats

T Baglioni, A Locatelli, P Sartorelli, T Simonic
  • PMID: 277435

Influence of age and cortisone treatment on two intestinal lysosomal hydrolases in young rats

T Baglioni et al. Ital J Biochem. 1978 Jan-Feb.

Abstract

The effects of cortisone acetate injected i.p. on acid phosphatase and beta-glucuronidase in the small intestine mucosa of two groups of rats aging 12-14 and 20-22 days are reported. The following results are obtained: a) Total and free activities of the two enzymes show age-dependent differences. b) Cortisone acetate causes a very marked decrease of the enzymic activities only in the younger rats while being ineffective on the older ones. c) The kinetics of the enzyme release at 37 degrees C appear independent either of age or of cortisone injection. d) The "in vitro" lysosome labilizing treatments are ineffective.

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