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Editorial
. 2016 Sep;8(9):2383-2386.
doi: 10.21037/jtd.2016.08.92.

Dual bronchodilation and exacerbations of COPD

Mario Cazzola  1 , Josuel Ora  1 , Ermanno Puxeddu  1
Affiliations
Editorial

Dual bronchodilation and exacerbations of COPD

Mario Cazzola et al. J Thorac Dis. 2016 Sep.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest to declare.

Comment on

  • Indacaterol-Glycopyrronium versus Salmeterol-Fluticasone for COPD.
    Wedzicha JA, Banerji D, Chapman KR, Vestbo J, Roche N, Ayers RT, Thach C, Fogel R, Patalano F, Vogelmeier CF; FLAME Investigators. Wedzicha JA, et al. N Engl J Med. 2016 Jun 9;374(23):2222-34. doi: 10.1056/NEJMoa1516385. Epub 2016 May 15. N Engl J Med. 2016. PMID: 27181606 Clinical Trial.

References

    1. Global Strategy for the Diagnosis, Management and Prevention of COPD. Global Initiative for Chronic Obstructive Lung Disease. Available online: http://goldcopd.org/ - PubMed
    1. Wedzicha JA, Decramer M, Ficker JH, et al. Analysis of chronic obstructive pulmonary disease exacerbations with the dual bronchodilator QVA149 compared with glycopyrronium and tiotropium (SPARK): a randomised, double-blind, parallel-group study. Lancet Respir Med 2013;1:199-209. 10.1016/S2213-2600(13)70052-3 - DOI - PubMed
    1. Calzetta L, Rogliani P, Matera MG, et al. A Systematic Review With Meta-Analysis of Dual Bronchodilation With LAMA/LABA for the Treatment of Stable COPD. Chest 2016;149:1181-96. 10.1016/j.chest.2016.02.646 - DOI - PubMed
    1. Calzetta L, Matera MG, Cazzola M. Pharmacological interaction between LABAs and LAMAs in the airways: optimizing synergy. Eur J Pharmacol 2015;761:168-73. 10.1016/j.ejphar.2015.05.020 - DOI - PubMed
    1. Cazzola M, Calzetta L, Segreti A, et al. Translational Study Searching for Synergy between Glycopyrronium and Indacaterol. COPD 2015;12:175-81. 10.3109/15412555.2014.922172 - DOI - PubMed