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Case Reports
. 1989 Jul;48(7):609-10.
doi: 10.1136/ard.48.7.609.

Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis

B Fishel  1 , M Tishler, D Caspi, M Yaron
Affiliations
Case Reports

Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis

B Fishel et al. Ann Rheum Dis. 1989 Jul.

Abstract

A 65 year old woman with rheumatoid arthritis developed marrow aplasia and jaundice owing to D-penicillamine treatment. Recovery of bone marrow was ineffective, and the patient finally died despite intensive therapeutic measures. The rare coexistence of myelotoxicity and hepatotoxicity is presented and discussed.

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References

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