Do p38 mitogen-activated protein kinase inhibitors have a future for the treatment of cardiovascular disease?

Affiliations

¹ Centre of Cardiovascular Research and Education in Therapeutics, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.

Comment

Andrew R Kompa. J Thorac Dis. 2016 Sep.

. 2016 Sep;8(9):E1068-E1071.

doi: 10.21037/jtd.2016.07.94.

¹ Centre of Cardiovascular Research and Education in Therapeutics, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.

No abstract available

Conflict of interest statement

The author has no conflicts of interest to declare.

Effect of Losmapimod on Cardiovascular Outcomes in Patients Hospitalized With Acute Myocardial Infarction: A Randomized Clinical Trial.
O'Donoghue ML, Glaser R, Cavender MA, Aylward PE, Bonaca MP, Budaj A, Davies RY, Dellborg M, Fox KA, Gutierrez JA, Hamm C, Kiss RG, Kovar F, Kuder JF, Im KA, Lepore JJ, Lopez-Sendon JL, Ophuis TO, Parkhomenko A, Shannon JB, Spinar J, Tanguay JF, Ruda M, Steg PG, Theroux P, Wiviott SD, Laws I, Sabatine MS, Morrow DA; LATITUDE-TIMI 60 Investigators. O'Donoghue ML, et al. JAMA. 2016 Apr 19;315(15):1591-9. doi: 10.1001/jama.2016.3609. JAMA. 2016. PMID: 27043082 Clinical Trial.

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