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Review
. 2016 Nov;5(11):3128-3139.
doi: 10.1002/cam4.861. Epub 2016 Oct 17.

Mechanisms and therapeutic effectiveness of pulsed electromagnetic field therapy in oncology

Maria Vadalà  1 , Julio Cesar Morales-Medina  2 , Annamaria Vallelunga  3 , Beniamino Palmieri  1 , Carmen Laurino  1 , Tommaso Iannitti  4
Affiliations
Review

Mechanisms and therapeutic effectiveness of pulsed electromagnetic field therapy in oncology

Maria Vadalà et al. Cancer Med. 2016 Nov.

Abstract

Cancer is one of the most common causes of death worldwide. Available treatments are associated with numerous side effects and only a low percentage of patients achieve complete remission. Therefore, there is a strong need for new therapeutic strategies. In this regard, pulsed electromagnetic field (PEMF) therapy presents several potential advantages including non-invasiveness, safety, lack of toxicity for non-cancerous cells, and the possibility of being combined with other available therapies. Indeed, PEMF stimulation has already been used in the context of various cancer types including skin, breast, prostate, hepatocellular, lung, ovarian, pancreatic, bladder, thyroid, and colon cancer in vitro and in vivo. At present, only limited application of PEMF in cancer has been documented in humans. In this article, we review the experimental and clinical evidence of PEMF therapy discussing future perspectives in its use in oncology.

Keywords: Cancer; electromagnetic therapy; oncology; pulsed electromagnetic fields; tumor-specific frequencies.

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