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. 2016 Sep;38(9):428-435.
doi: 10.1055/s-0036-1593410. Epub 2016 Oct 17.

Reference Ranges of Fetal Cerebral Lateral Ventricle Parameters by Ultrasonography

Aderemi Ishola  1 , Christianah Mopelola Asaleye  1 , Oluwagbemiga Oluwole Ayoola  1 , Olabisi Morebise Loto  2 , Bukunmi Michael Idowu  1
Affiliations

Reference Ranges of Fetal Cerebral Lateral Ventricle Parameters by Ultrasonography

Aderemi Ishola et al. Rev Bras Ginecol Obstet. 2016 Sep.

Abstract
in English, Undetermined language

Objectives This study was done to evaluate the normal fetal cerebral lateral ventricle dimensions with transabdominal ultrasonography. The atrial width (AW), ventricle-to-choroid measurement (V-C), ventricle-to-hemisphere ratio (VHR), and combined anterior horn measurement (CAHM) were taken. Methods This was a cross-sectional study involving 400 normal singleton pregnant subjects whose gestational ages were between 14 and 40 weeks. Transabdominal sonography was performed to obtain the values of the fetal cerebral lateral ventricle (FCLV) parameters. Data were reported as mean ± standard deviation (SD) for continuous variables. The degrees of correlation between FCLV parameters and the estimated gestational age (EGA) were obtained using Pearson's correlation. Regression equations were used to generate the reference limits for the FCLV measurements. Results The values of AW, V-C measurements and CAHM increased with advancing gestation. The mean values of the AW, V-C and CAHM from 14 to 40 weeks increased from 6.60 ± 0.94 mm to 9.75 ± 0.07 mm (R2 = 0.114), 0.80 ± 0.00 mm to 1.90 ± 0.14 mm (R2 = 0.266), and 6.95 ± 0.06 mm to 23.07 ± 4.02 mm (R2 = 0.692) respectively, while the mean VHR decreased from 61.20 ± 1.60% to 42.84 ± 2.91% (R2 = 0.706) over the same period. Conclusion The AW, V-C, and CAHM increase, while VHR decreases with advancing gestation.

Resumo: Objetivos O presente estudo objetiva avaliar as dimensões do ventrículo lateral de cérebros fetais por meio de ultrassonografia transabdominal. Foram medidos a largura do átrio (LA), a medida do ventrículo ao coroide (V-C), a razão ventrículo/ hemisfério (RVH), e a medida dos cornos anteriores combinados (CAC).

Métodos Estudo transversal com 400 grávidas de único feto com idades gestacionais entre 14 e 40 semanas. Sonografias transabdominais foram realizadas para obter os valores dos parâmetros do ventrículo lateral de cérebros fetais (VLCF). Dados foram apresentados em média ± desvio padrão para variáveis contínuas. Os graus de correlação entre parâmetros de VLCF e idade gestacional estimada foram obtidos usando a correlação de Pearson. Equações de regressão foram usadas para gerar as referências-limite para medidas de VLCF.

Resultados Os valores de LA, medida do V-C e CAC aumentaram com o avanço da gestação. Os valores médios de LA, V-C e CAC de 14 a 40 semanas aumentaram de 6,60 ± 0,94 mm a 9,75 ± 0,07 mm (R2 = 0,114), de 0,80 ± 0,00 mm a 1,90 ± 0,14 mm (R2 = 0,266), e de 6,95 ± 0,06 mm a 23,07 ± 4,02 mm (R2 = 0,692), respectivamente, enquanto a RVH média diminuiu de 61,20 ± 1,60% para 42,84 ± 2,91% (R2 = 0,706) no mesmo período.

Conclusão A LA, V-C, e CAC aumentaram, enquanto a RVH diminuiu com o avanço da gestação.

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Conflict of interest statement

Conflict(s) of Interest None to declare.

Figures

Fig. 1
Fig. 1
Schematic diagram of the axial transventricular ultrasound image of a fetal brain showing the landmarks for obtaining measurements. 1. Atrial width (AW): A–B. 2. Ventricle-to-choroid measurement (V-C): C. 3. Ventricle to hemispheric ratio (VHR): DE/DF. 4. Combined anterior horn measurement (CAHM): G–H. 5. DE: Lateral ventricular width (LVW). 6. DF: Cerebral hemisphere width (CHW). 7. CSP: Cavum septum pellucidum.
Fig. 2
Fig. 2
Scatter plot of AW versus estimated gestational age (EGA), with the 5th, 50th and 95th percentile values.
Fig. 3
Fig. 3
Scatter plot of V-C measurement versus EGA, with the 5th, 50th and 95th percentile values.
Fig. 4
Fig. 4
Scatter plot of CAHM versus EGA, with the 5th, 50th and 95th percentile values.
Fig. 5
Fig. 5
Scatter plot of VHR versus EGA, with the 5th, 50th and 95th percentile values.
See this image and copyright information in PMC

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