Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Meta-Analysis
. 2016 Oct 18;17(1):430.
doi: 10.1186/s12891-016-1274-6.

The new Zero-P implant can effectively reduce the risk of postoperative dysphagia and complications compared with the traditional anterior cage and plate: a systematic review and meta-analysis

Mengchen Yin  1   2 , Junming Ma  1 , Quan Huang  2 , Ye Xia  1 , Qixing Shen  1 , Chenglong Zhao  2 , Jun Tao  2 , Ni Chen  1 , Zhingxing Yu  1 , Jie Ye  1 , Wen Mo  3 , Jianru Xiao  4
Affiliations
Meta-Analysis

The new Zero-P implant can effectively reduce the risk of postoperative dysphagia and complications compared with the traditional anterior cage and plate: a systematic review and meta-analysis

Mengchen Yin et al. BMC Musculoskelet Disord. .

Abstract

Background: The low-profile angle-stable spacer Zero-P is a new kind of cervical fusion system that is claimed to limit the potential drawbacks and complications. The purpose of this meta-analysis was to compare the clinical and radiological results of the new Zero-P implant with those of the traditional anterior cage and plate in the treatment of symptomatic cervical spondylosis, and provides clinicians with evidence on which to base their clinical decision making.

Methods: The following electronic databases were searched: PMedline, PubMed, EMBASE, the Cochrane Central Register of Controlled Trials, Evidence Based Medicine Reviews, VIP, and CNKI. Conference posters and abstracts were also electronically searched. The efficacy was evaluated in intraoperative time, intraoperative blood loss, fusion rate and dysphagia.

Results: For intraoperative time and intraoperative blood loss, the meta-analysis revealed that the Zero-P surgical technique is not superior to the cage and plate technique . For fusion rate, the two techniques both had good bone fusion, however, this difference is not statistically significant. For decrease of JOA and dysphagia, the pooled data showed that the Zero-P surgical technique is superior to the cage and plate technique.

Conclusions: Zero-P interbody fusion can attain good clinical efficacy and a satisfactory fusion rate in the treatment of symptomatic cervical spondylosis. It also can effectively reduce the risk of postoperative dysphagia and its complications. However, owing to the lack of long-term follow-up, its long-term efficacy remains unknown.

Keywords: Cage; Cervical spine; Cervical spondylosis; Systematic review; Zero-P plate.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Select process
Fig. 2
Fig. 2
Zero-P versus cage + plate on intraoperative time
Fig. 3
Fig. 3
Zero-P versus cage + plate on intraoperative blood loss
Fig. 4
Fig. 4
Zero-P versus cage + plate on intraoperative decrease of JOA score
Fig. 5
Fig. 5
Zero-P versus cage + plate on dysphagia early postoperative
Fig. 6
Fig. 6
Zero-P versus cage + plate on dysphagia at last follow-up
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Tracy JA, Bartleson JD. Cervical spondylotic myelopathy. Neurologist. 2010;16(3):176–187. doi: 10.1097/NRL.0b013e3181da3a29. - DOI - PubMed
    1. Vanek P, Bradac O, DeLacy P, Saur K, Belsan T, Benes V. Comparison of 3 fusion techniques in the treatment of the degenerative cervical spine disease. Is stand-alone autograft really the “gold standard?”: prospective study with 2-year follow-up. Spine (Phila Pa 1976) 2012;37(19):1645–1651. doi: 10.1097/BRS.0b013e31825413fe. - DOI - PubMed
    1. Korinth MC. Treatment of cervical degenerative disc disease–current status and trends. Zentralbl Neurochir. 2008;69(3):113–124. doi: 10.1055/s-2008-1081201. - DOI - PubMed
    1. Le H, Thongtrangan I, Kim DH. Historical review of cervical arthroplasty. Neurosurg Focus. 2004;17(3):E1. doi: 10.3171/foc.2004.17.3.1. - DOI - PubMed
    1. Matz PG, Ryken TC, Groff MW, et al. Techniques for anterior cervical decompression for radiculopathy. J Neurosurg Spine. 2009;11(2):183–197. doi: 10.3171/2009.2.SPINE08721. - DOI - PubMed

MeSH terms