Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2016 Jul-Aug;48(4):455-457.
doi: 10.4103/0253-7613.186216.

A clinically suspected case of Anaphylactoid reaction to vitamin K injection in a child - a case report and review of literature

Bharat Choudhary  1 , Sweta Kumari  2 , Bhavna Dhingra  1 , Ratinder Jhaj  2
Affiliations
Case Reports

A clinically suspected case of Anaphylactoid reaction to vitamin K injection in a child - a case report and review of literature

Bharat Choudhary et al. Indian J Pharmacol. 2016 Jul-Aug.

Abstract

Vitamin K is commonly indicated in pediatric patients with coagulopathies. Its commercial preparations are available in the market since long. Minor complications are very well-known, but life-threatening events are rarely reported in children. We present a case of 8-year-old child who developed life-threatening event following intravenous Vitamin K injection. She was survived after cardiopulmonary resuscitation. The reaction was most probably due to anaphylactoid reaction to Vitamin K.

Keywords: Adverse reaction; Vitamin K; anaphylactoid reaction; children.

PubMed Disclaimer

Similar articles

See all similar articles

References

    1. Johnson BC. Post-translational carboxylation of preprothrombin. Mol Cell Biochem. 1981;38(Pt 1):77–121. - PubMed
    1. Bhat RV, Deshmukh CT. A study of Vitamin K status in children on prolonged antibiotic therapy. Indian Pediatr. 2003;40:36–40. - PubMed
    1. Aziz F, Patil P. Role of prophylactic Vitamin K in preventing antibiotic induced hypoprothrombinemia. Indian J Pediatr. 2015;82:363–7. - PubMed
    1. Riegert-Johnson DL, Volcheck GW. The incidence of anaphylaxis following intravenous phytonadione (Vitamin K1): A 5-year retrospective review. Ann Allergy Asthma Immunol. 2002;89:400–6. - PubMed
    1. Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al. Amethod for estimating the probability of adverse drug reactions. Clin Pharmacol Ther. 1981;30:239–45. - PubMed

Publication types

MeSH terms