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. 2016 Oct 7;3(4):ofw183.
doi: 10.1093/ofid/ofw183. eCollection 2016 Oct.

Fusarium Osteomyelitis in a Patient With Pearson Syndrome: Case Report and Review of the Literature

Rachael M Hiebert  1 , Robert C Welliver  2 , Zhongxin Yu  3
Affiliations

Fusarium Osteomyelitis in a Patient With Pearson Syndrome: Case Report and Review of the Literature

Rachael M Hiebert et al. Open Forum Infect Dis. .

Abstract

Fusarium species are ubiquitous fungi causing a wide array of infections, including invasive disease in the immunosuppressed. We present a fusarium bone infection in a child with Pearson syndrome and review the literature. Ten cases of fusarium osteomyelitis were reported in the past 40 years, and we review the treatments.

Keywords: fusarium; immunocompromised; osteomyelitis.

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Figures

Figure 1.
Figure 1.
A, Histological sections of the tissue with focal abscess (right lower portion of the picture) with occasional multinucleated giant cells (left upper portion of the picture) and focal chronic inflammation with sequestrated fragment of necrotic bone (inset), consistent with acute and chronic osteomyelitis (Hematoxylin and eosin, ×200). B, Histological section of the articular cartilage within the lesion containing multiple septated hyaline hyphae, some of which are indicated by arrows (H&E, ×600). C and D, Gomori methenamine silver stain reveals irregular septate hyphae with focal acute angle branching ([C]: GMS, ×400; [D]: GMS, x600).
See this image and copyright information in PMC

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