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. 2017 Mar;33(3):203-210.
doi: 10.1089/AID.2016.0021. Epub 2016 Nov 17.

A Proposed Framework for the Implementation of Early Infant Diagnosis Point-of-Care

Karidia Diallo  1 , Surbhi Modi  2 , Mackenzie Hurlston  1 , R Suzanne Beard  1 , John N Nkengasong  1
Affiliations

A Proposed Framework for the Implementation of Early Infant Diagnosis Point-of-Care

Karidia Diallo et al. AIDS Res Hum Retroviruses. 2017 Mar.

Abstract

Early diagnosis of HIV infection in infants and children remains a challenge in resource-limited settings, with approximately half of all HIV-exposed infants receiving virological testing for HIV by the recommended age of 2 months in 2015. To reduce morbidity and mortality among HIV-infected children and close the treatment gap for HIV-infected children, there is an urgent need to evaluate existing programmatic and laboratory practices for early infant diagnosis and introduce strategies to improve identification of HIV-exposed infants and ensure access to systematic, early HIV testing, with early linkage to treatment for HIV-infected infants. This article describes progress made in follow-up of HIV-exposed infants since 2006, including remaining unmet laboratory and programmatic needs, and recommends strategies for improvement, especially those related to the implementation of point-of-care technology for early infant diagnosis.

Keywords: HIV; early infant diagnosis; near point-of-care; point-of-care.

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Conflict of interest statement

No competing financial interests exist.

Figures

<b>FIG. 1.</b>
FIG. 1.
Early infant diagnosis testing pyramid stratified by tiered laboratory level, infrastructure, and staff capacity.
<b>FIG. 2.</b>
FIG. 2.
Building an efficient early infant diagnosis laboratory network within existing infrastructure.
See this image and copyright information in PMC

References

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