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. 1989 Sep;28(9):1637-43.
doi: 10.1002/bip.360280912.

On the cooperative binding of large ligands to a one-dimensional homogeneous lattice: the generalized three-state lattice model

On the cooperative binding of large ligands to a one-dimensional homogeneous lattice: the generalized three-state lattice model

W Bujalowski et al. Biopolymers. 1989 Sep.

Abstract

We present the general secular equation for three-state lattice models for the cooperative binding of large ligands to a one-dimensional lattice. In addition, a closed-form expression for the isotherm is also obtained, that can be used with all values of the cooperativity parameter omega(0 less than omega less than infinity) thus eliminating the need for multiple equations.

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